Paul was a man who suffered the loss of everything, according to his own claim. Yet any loss he counted pure gain.
The key to this transforming of earthly losses into heavenly gains is love. What do we love?
If our hearts are set on people and possessions and position, the loss of those will indeed be irreparable. To the man or woman whose heart is set on Christ no loss on earth can be irreparable.
It may shock us for the moment. We may feel hurt, outraged, desolate, helpless. That is our humanity. But the Lord can show us the "long view," the incalculable gain in spiritual and eternal terms, if we love Him above all. Everything that belongs to us belongs also to Him.
Everything that belongs to Him belongs also to us. What, then, can we finally lose?
If we lose not Christ Himself, we have finally lost nothing, for He is our treasure and He has our hearts.